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Effects of a single mutation in Chikungunya virus non-structural protein on virus infection in Aedes Albopictus and Mammalian Cell Lines

Jolene Fu, Yin Ling
UM Research Repository · Papers · License: CC BY-NC-ND 4.0
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aedes-albopictuschikungunya-viruspublic-health-education-and-promotionsoutheast-asiavirus-diseases
Chikungunya virus (CHIKV) has caused large-scale epidemics of fever, rash and arthritis since 2004. This unprecedented re-emergence has been mainly associated with mutations in genes encoding structural envelope proteins, providing increased fitness in the secondary vector Aedes (Ae.) albopictus. In
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