bioRxiv / medRxiv
open access
Patient-derived monoclonal anti-HPA-1a can induce platelet activation through FcγRIIa
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a pregnancy-associated disorder caused by maternal alloantibodies targeting paternally inherited human platelet antigens (HPAs). These antibodies traverse the placenta and bind to fetal platelets, causing thrombocytopenia and potentially seve
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