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A Study of Cebranopadol for Opioid Withdrawal Symptoms in Adults With Chronic Pain

Adneuris Therapeutics, Inc. · 2026
ClinicalTrials.gov · Datasets · License: Public Domain · 2026
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chronic-painpain
This Phase 2 study will evaluate whether multiple doses of cebranopadol suppress opioid withdrawal signs and symptoms compared with placebo in adults with chronic pain who are physically dependent on prescribed opioids. Participants whose physical dependence is confirmed will be assigned by chance to one of two cebranopadol dose regimens or matching placebo. The study will also evaluate pain, safety and tolerability, and cebranopadol pharmacokinetics.
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