MTHFR Mutation and Concentration of B12,Folic Acid,Homocysteine and HS CRP in the Blood of Pregnant Women With GDM.

Research hypothesis: * pregnant women with gestational diabetes have elevated serum CRP values and homocysteine compared to pregnant women with normal glucose metabolism * Elevated CRP and homocysteine values are associated with poorer perinatal outcome. * reduced concentrations of folic acid and vitamin B 12 are associated with higher homocitein values * Carriers of the MTHFR gene mutation have higher homocysteine concentrations