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Resmetirom in Patients With MASH and HFpEF

Madrigal Pharmaceuticals, Inc. · 2026
ClinicalTrials.gov · Datasets · License: Public Domain · 2026
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mash
This Phase 1b multicenter randomized double-blind placebo-controlled study evaluates the safety, tolerability and hepatic pharmacodynamic effects of resmetirom in adults with metabolic dysfunction-associated steatohepatitis (MASH) and heart failure with preserved ejection fraction (HFpEF). Participants are randomized 2:1 to resmetirom or placebo for 24 weeks.
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