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Does complement factor B have a role in the pathogenesis of atypical HUS?

David Kavanagh (22732733) et al.
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Atypical haemolytic uraemic syndrome (aHUS) is a disorder of complement dysregulation. Because complement factor B (fB) carries the catalytic site of the alternative pathway convertase we examined it as both a potential candidate gene and modifier in the pathogenesis of aHUS. No factor B gene (BF) m
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