bioRxiv / medRxiv
open access
Redefining Non Invasive Post Transplant Surveillance: A Bayesian Meta Analysis and Decision Curve Framework for Donor Derived Cell Free DNA in Heart Transplantation
Donor-derived cell-free DNA (dd-cfDNA) is increasingly used for post transplantation non-invasive surveillance; however, its clinical interpretation remains inconsistent, with widely ranging thresholds and is typically applied as a single binary cutoff in literature. The optimal decision framework f
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