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Phase I Study of Cetuximab in Combination With 5-fluoruracil, Mitomycin C and Radiotherapy in Patients With Anal Cancer Stage T2 (>4 cm) - T4 N0-3 M0 or Any T N2-3 M0

Lund University Hospital · 2012
ClinicalTrials.gov · Datasets · License: Public Domain · 2012
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radiotherapy
* To establish maximum tolerated dose of the two cytotoxic drugs 5-fluoruracil and mitomycin C when given together with the antibody cetuximab in patients with locally advanced cancer in the anal region * To evaluate acute toxicity * To evaluate late toxicity * To evaluate response rate * To evaluate recurrence free survival * To evaluate overall survival
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