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Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole

M.D. Anderson Cancer Center · 1994
ClinicalTrials.gov · Datasets · License: Public Domain · 1994
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head-and-neck-neoplasmsnaneoplasmsquamous-cell-carcinomasquamous-cell-carcinoma-of-head-and-neck
The purpose of this clinical research study is to answer the following questions using 18F-fluoromisonidazole as an imaging agent: 1. Do cells exist in human tumors that are at very low oxygen levels (hypoxic cells)? 2. If hypoxic cells exist in human tumors, do they effect the ability of radiotherapy to control human tumors? 3. Can Positron Emission Tomography (PET scanning) detect hypoxic cells in human tumors?
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