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A Post-Transcriptional Feedback Mechanism for Noise Suppression and Fate Stabilization

Hansen, Maike MK et al.
eScholarship · Papers
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31-biological-sciences-for-2020feedback
Diverse biological systems utilize fluctuations ("noise") in gene expression to drive lineage-commitment decisions. However, once a commitment is made, noise becomes detrimental to reliable function, and the mechanisms enabling post-commitment noise suppression are unclear. Here, we find that archit
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