bioRxiv / medRxiv
open access
Elevated phosphorylated α-synuclein and phosphorylated tau in Lrrk2 p.G2019S-mutant mice following influenza A pneumonitis
Background: Influenza virus exposure elevates the incidence of parkinsonism. We and others previously discovered that allelic variants at the Parkinson's-linked LRRK2 locus modulate host responses to virulent microbes. Objective: We asked whether Lrrk2 mutations modify disease outcomes in adult anim
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