bioRxiv / medRxiv
open access
Variation in multiple classes of simple sequence repeats can alter drug susceptibility in Mycobacterium tuberculosis
Insertions and deletions (INDELs) in simple sequence repeats (SSRs) generate relatively high-frequency reversible genetic changes that facilitate bacterial adaptation to changing environments. Analyses of global Mycobacterium tuberculosis (Mtb) isolates indicate that many SSRs are under diversifying
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