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CHIP and Residual Cardiovascular Event Tendency After Smoking Cessation

Shenyang Northern Hospital · 2021
ClinicalTrials.gov · Datasets · License: Public Domain · 2021
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smoking-cessation
In order to identify the association between clonal hematopoiesis of indeterminate potential (CHIP) and cardiovascular risks after smoking cessation, this study intends to recruit ACS patients undergoing complete revascularization and perform whole-exome sequencing for enrolled patients to identify the prevalence of CHIP mutations. After 1-year follow-up, the relationship of presence of CHIP mutations and the occurrence of MACCEs will be explored, irrespective of smoking cessation or not. CHIP may be a potential risk factor of poor prognosis of ACS.
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