HAL (France)
open access
Loss of SNORD104-guided rRNA methylation promotes early adaptation to crizotinib in lung adenocarcinoma
The ribosome, long considered an invariant actor of gene expression, recently emerged as a contributor to translational control through chemical modifications of ribosomal RNAs (rRNAs). These modifications are guided by small nucleolar RNAs (snoRNAs), which direct modifying enzymes to specific rRNA
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