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Molecular, cellular, and clinical aspects of myofibrillar myopathy caused by HSPB8 frameshift mutations
HSPB8 belongs to the small heat shock protein family, which comprises ten chaperones with molecular weights below 29 kDa. HSPB8 is broadly expressed across human tissues, with the highest levels in skeletal muscles, the cardiac muscle, and the nervous system. In muscles, HSPB8 plays a crucial role i
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