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Identification and engineering of natural alleles that increase protein secretion in Saccharomyces cerevisiae and Komagataella phaffii
Recombinant protein production in microbial cell factories like Saccharomyces cerevisiae or Komagataelle phaffii is a cornerstone of modern biotechnology. However, yields are often suboptimal and attempts to increase secretion have shown mixed and target-specific results. To identify broader enginee
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