bioRxiv / medRxiv
open access
Early adversity promotes adolescent avoidance behavior by enhancing prefrontal-amygdala communication through CRH+ glutamatergic neurons
Early life adversity (ELA) has lasting impacts on emotion circuit function1. Exposure to early maltreatment, neglect, or household instability is associated with enduring alterations in threat evaluation and response, hallmarks of mood and anxiety disorders2-4. These alterations often emerge during
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