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Mechanisms Of Orbitofrontal Stimulation in Depression

Subha Subramanian · 2026
ClinicalTrials.gov · Datasets · License: Public Domain · 2026
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depressionna
The orbitofrontal cortex (OFC), a region involved in emotional regulation, decision making, and reward processing, is a key area linked to antidepressant response. This study tests whether noninvasive stimulation of the OFC using transcranial magnetic stimulation (TMS) can improve depressive symptoms. TMS uses magnetic fields generated by a coil placed next to the scalp to alter brain activity.
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