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Sympathetic Activity in Patients With End-stage Renal Disease on Peritoneal Dialysis

Ottawa Hospital Research Institute · 2007
ClinicalTrials.gov · Datasets · License: Public Domain · 2007
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leptinperitoneal-dialysis
Hypothesis: Patients starting peritoneal dialysis with a glucose-based regimen have high sympathetic activity in response to an increase in leptin and insulin. Converting patients from a regimen of only glucose containing dialysate to a regimen with non-glucose-based solution, icodextrin, will reduce the insulin and leptin levels and will reverse dialysis-induced increases in sympathetic activity.
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