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Safety & Radiation Distribution Study of Cotara® in Patients With Recurrent Glioblastoma Multiforme

Peregrine Pharmaceuticals · 2006
ClinicalTrials.gov · Datasets · License: Public Domain · 2006
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brain-cancermonoclonal-antibody
RATIONALE: Cotara® is an experimental new treatment that links a radioactive isotope (iodine 131) to a targeted monoclonal antibody. This monoclonal antibody is designed to bind tumor cells and deliver radiation directly to the center of the tumor mass while minimizing effects on normal tissues. Cotara® thus literally destroys the tumor "from the inside out." This may be an effective treatment for glioblastoma multiforme, a malignant type of brain cancer. PURPOSE: This trial is studying the safety and radiation distribution of Cotara® in patients with recurrent glioblastoma multiforme.
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