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Rewiring redox defense: Nrf2-driven antioxidant signaling as a gateway to programmed cell death activation in colorectal cancer
Nuclear factor erythroid 2-related factor 2 (Nrf2), a master regulator of antioxidant and phase II detoxification genes, plays a dual role in colorectal cancer (CRC) progression by maintaining redox homeostasis while paradoxically fostering chemoresistance. Programmed cell death (PCD) pathways, incl
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