Europe PMC
open access
Gut microbiota-mediated uric acid metabolism: Novel insights for developing urate-lowering and anti-gout medications
Hyperuricemia, caused by purine metabolism dysfunction and impaired uric acid excretion, is increasing in prevalence globally. Current urate-lowering drugs have limitations in safety and applicability. The gut, which is central to uric acid production and excretion, hosts microbiota closely linked t
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