Zenodo (CERN)
open access
Separating Lactate Chromatin Chemistry from PGC-1alpha Biogenesis Claims
**Background:** Lactate can alter nuclear chromatin chemistry, nuclear redox state, reactive oxygen species (ROS), hypoxia-inducible factor 1alpha (HIF-1alpha), SIRT1 activity and PGC-1alpha-linked mitochondrial markers, but those endpoints are often compressed into a single lactate-to-PGC-1alpha
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