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In Vivo Study of Interactions Between the Endocannabinoid System and the Corticotropic Axis in Man
Working hypothesis: the interactions between the endogenous endocannabinoïds (ECS) - and cortisol, the end product of the Hypothalamo-Pituitary-Adrenal (HPA) axis may play a role in the pathophysiology of Cushing's syndrome. The investigators speculate that: * acute or chronic variations in plasma cortisol may induce changes in the activity of the ECS * that there is a circadian rhythm of the ECS driven by the rythm of plasma cortisol
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