Evaluation of Blood Vessel Formation in Endocrine Tumors

Background: * Tumors depend on blood vessels to provide the nourishment that allows them to grow. * Thyroid, parathyroid, adrenal gland and pancreatic neuroendocrine tumors are among the tumors that contain the most blood vessels. Thus, endocrine tumors are important for the study of new blood vessel formation in tumors. Objectives: -To obtain tissues from endocrine tumors for examination to determine how they differ from normal tissue. Eligibility: -Patients who are scheduled for surgery to remove an endocrine tumor, those in or around the thyroid, parathyroid, adrenal gland, pancreas, or any neuroendocrine tissue. Design: * Tissues will be obtained from patients during surgery to remove thyroid, parathyroid, adrenal, pancreas, or neuroendocrine tumors. * About 400 patients will be enrolled in the study over a period of 5 years.