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Bahir Dar Child Development Study, Ethiopia

Brigham and Women's Hospital · 2024
ClinicalTrials.gov · Datasets · License: Public Domain · 2024
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africabehaviorchilddevelopmentneurodevelopmentsocial
The goal of this observational study is to learn about typical neurodevelopment in children aged 6 months to 5 years who live in Bahir Dar, Ethiopia. The main aims of the study are: Aim 1: To characterize typical neurodevelopment as measured by i) brain volume using low-field MRI and ii) scores on behavioral assessments of early child neurodevelopment. Aim 2: To characterize typical pre-academic school skills in early childhood as measured by tasks of visual processing, reasoning, verbal expression and school readiness. Aim 3: To identify factors influencing child development in a community in Bahir Dar, Amhara region of Ethiopia, as measured by validated measures of maternal mental health, home environment, and childhood adversity. Participants will complete one low-field MRI scan at enrollment, have a hemoglobin blood test, and undergo age-appropriate neurodevelopmental assessments and surveys that may include: * WHO Global Scales for Early Development (GSED) \[ages 6 - 36 months\] * Tasks of visual reasoning and verbal expression \[ages 48-60 months\] * Executive Functions test using the tablet-based NIH Toolbox \[ages 48-60 months\] * School Readiness questionnaire assessing knowledge of literacy, numeracy, early reading, crystallized knowledge, memory, and self-regulation \[ages 48-60 months\] * Maternal report of child's motor, cognitive and socioemotional skillsChild Anthropometrics assessment Additional assessments of the participant's family and environment will include * Medical History questionnaire * Family socioeconomic status * Maternal Mental Health * Recent Life Events and hardship * Home Environment and Parenting UNICEF's MICs Family Care Indicators) * Food security and feeding practices
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