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A Multiscale Kinetic Model of DNA Damage Signalling and Repair under Combined Proton and Nanoparticle Exposure
We present a multiscale kinetic framework for predicting the induction, processing, and biological consequences of DNA double-strand breaks (DSBs) in AG1522 human fibroblasts exposed to combined proton and 15-nm GNP irradiation. The model connects proton dose and linear energy transfer (LET), perinu
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