HAL (France)
open access
Convergent S318T substitution in ADC enzymes contributes to reduced meropenem susceptibility in epidemic IC2 Acinetobacter baumannii
Carbapenem resistance in Acinetobacter baumannii is usually mediated by acquired carbapenemases. Here we investigated an alternative mechanism involving variants of the intrinsic Acinetobacter-derived cephalosporinase (ADC).
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