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The Impact of Hypoxia and Androgen Inhibition on Prostate Cancer Cell Dedifferentiation and the DNA Damage Repair Response at Telomeres
Long-term Androgen deprivation therapy (ADT) is used to treat Prostate cancer (PCa) but is often met with resistance & the development of Neuroendocrine (NE) PCa which is rarer but more aggressive. Antiandrogens are a part of ADT that work to inhibit androgen receptor in PCa cells. In vitro, PCa cel
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