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Pharmacogenetics in Non Small Cell Lung Cancer

Ain Shams University · 2018
ClinicalTrials.gov · Datasets · License: Public Domain · 2018
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cisplatinlung-cancernon-small-cell-lung-cancerpharmacogenetics
Study the effect of genetic polymorphism in the membrane copper transporter 1 protein \[CTR1; encoded by the solute carrier family 31 member 1 gene (SLC31A1 gene)\] and its genetic expression levels on the clinical outcome of cisplatin-based regimen used in the treatment of Non-Small Cell Lung Cancer (NSCLC) in terms of : * Treatment response : partial response (PR) / complete response (CR) and Progression-free survival (PFS) * Treatment resistance : stationary disease (SD) or progressed disease * Frequency and severity of regimen related toxicity
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