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Pulse Radiotherapy to Overcome Metastatic Immune System Evasion in Lung Cancer

Centre hospitalier de l'Université de Montréal (CHUM) · 2026
ClinicalTrials.gov · Datasets · License: Public Domain · 2026
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non-small-cell-lung-cancerradiotherapy
This phase I study aims to evaluate the safety and effectiveness of adaptive pulsed radiotherapy combined with immunotherapy in patients with metastatic non-small cell lung cancer (NSCLC) resistant to immune checkpoint inhibitors. The primary goal is to assess treatment-related toxicity, while secondary objectives include progression-free survival, overall survival, and quality of life. The study will enroll 32 patients.
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