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Acute Intervention with Sulforaphane-Smart®

Mª Jesús Periago · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
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bioavailabilityhealthy
The Sulforaphane-Smartt® formula is a pill, patented by the company INGREDALIA, prepared with broccoli by-products which have been concentrated and enriched in glucosinolates/isothiocyanates (GLS/ITCs). The goal of this intervention study with the Sulforaphane-Smartt® formula is to study the bioavailability of the bioactive compounds in normal weight and overweight adults. The main questions it aims to answer are: * Determine the absorption curve of the bioactive compounds (GLS/ITCs). * Analyze the metabolites in plasma and urine of the GLS/ITCs to know the bioavailability. This acute intervention is designed to take a single fasting dose of Sulforaphan-Smart®, collecting plasma and urine samples to study free and conjugated metabolites of GLS/ITC. There is not a comparison group, since the acute intervention study with the Sulforaphane-Smart® is designed to determine the bioavailability of the bioactive compounds (GLS/ITCs).
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