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Molecular and Physiological Regulation of ACE2: Interaction with TMPRSS2, Glycosylation-Dependent Processing, and Roles in Skin Pigmentation

Qiu, Yue
edoc-Server · Papers · License: CC BY 4.0
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Das Angiotensin-konvertierende Enzym 2 (ACE2) ist ein membrangebundenes Enzym des Renin-Angiotensin-Systems und der zelluläre Rezeptor für SARS-CoV-2. Für den Viruseintritt ist zudem die transmembrane Serinprotease TMPRSS2 erforderlich, die das Spike-Protein aktiviert und ACE2 spalten kann. Diese Di
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