Reln Haploinsufficiency Enhances Fentanyl‐Induced Locomotion and Dorsal Striatal Activity Without Affecting Opioid Reinforcement and Relapse‐Like Behavior

The Reln gene encodes the extracellular glycoprotein Reelin that regulates synaptic plasticity and activity-dependent gene expression with implication in several neuropsychiatric disorders, including substance use disorder. Although reduction of Reln expression has been associated with altered respo