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Successful Erlotinib Treatment for a Patient with Gefitinib-Related Hepatotoxicity and Lung Adenocarcinoma Refractory to Intermittently Administered Gefitinib

Nagano, Tatsuya(Division of Respiratory Medicine, Department of Internal Medicine) Kotani, Yoshikazu(Division of Respiratory Medicine, Department of Internal Medicine) Kobayashi, Kazuyuki(Division of Respiratory Medicine, Department of Internal Medicine) Katsurada, Masahiro(Division of Respiratory M
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A 73-year-old Japanese man was histologically diagnosed with lung adenocarcinoma harboring an exon 19 deletion in the epidermal growth factor receptor. The patient was treated with gefitinib for 6 weeks until he developed substantially elevated hepatic enzyme levels that resulted in the discontinuat
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