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Microglia integration into midbrain organoids: Origin matters

Verkerke, M. et al.
bioRxiv / medRxiv · Papers
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neuroscience
Midbrain organoids (MOs) can be powerful tools to study brain diseases, yet one shortcoming is the lack of microglia due to their mesodermal developmental origin. Previous studies have incorporated iPSC-derived microglia (iMG), but their immature phenotype restricts the applicability to model age-re
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