bioRxiv / medRxiv
open access
Machine Learning identification in patients with aortic valve stenosis of a myocardial miRNA signature predictive of reverse cardiac remodelling after valve replacement
BackgroundAortic stenosis (AS) is a valvular heart disease which imposes chronic pressure overload on the left ventricle (LV). Although LV remodelling may regress following aortic valve replacement, the molecular determinants of reverse remodelling remain poorly understood. This study develops a mac
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