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Brain Mechanisms of Overeating in Children

Penn State University · 2018
ClinicalTrials.gov · Datasets · License: Public Domain · 2018
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decision-makingfmrifunctional-magnetic-resonance-imaginginhibitionobesitypediatric-obesityworking-memory
The proposed research will follow healthy weight children who vary by family risk for obesity to identify the neurobiological and appetitive traits that are implicated in overeating and weight gain during the critical pre-adolescent period. The investigator's central hypothesis is that increased intake from large portions of energy dense foods is due in part to reduced activity in brain regions implicated in inhibitory control and decision making, combined with increased activity in reward processing pathways. To test this hypothesis, the investigators will recruit 120 healthy weight children, aged 7-8 years, at two levels of obesity risk (i.e., 60 high-risk and 60 low-risk) based on parent weight status. This will result in 240 participants: 120 children and their parents.
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