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Interferon‐α–Driven Stratification of B Cells Reveals Metabolic Reprogramming of Double‐Negative, Naïve, and Transitional Cell Subsets and Refines Molecular Classification in Sjögren's Disease

Cristian Iperi et al.
HAL (France) · Papers
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metabolismtranscriptomics
ABSTRACT Sjögren's disease (SjD) is a chronic autoimmune condition marked by lymphocytic infiltration of exocrine glands and production of autoantibodies such as anti‐SSA/Ro, anti‐SSB/La, and rheumatoid factor. B lymphocytes play a central role in disease pathogenesis, driving autoantibody productio
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