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KRASG12D Cells Override Homeostatic Cell Elimination Mechanisms in Adult Pancreas Via Wnt5a and Cell Dormancy

Salvador-Barbero, Beatriz et al.
PubMed Central · Reports · License: CC BY 4.0
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BACKGROUND & AIMS: The adult pancreas protects against cancer by actively expelling genetically mutated cells. Pancreatic cancer starts with cells carrying KRAS mutations; however, it is not clear how some KRAS mutant cells override cell elimination mechanisms to survive in tissues. METHODS: An in v
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