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Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid
Abstract13-cis-retinoic acid (isotretinoin, INN) is an oral pharmaceutical drug used for the treatment of skin acne, and is also a known teratogen. In this study, the molecular mechanisms underlying INN-induced developmental toxicity during early cardiac differentiation were investigated using both
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