bioRxiv / medRxiv
open access
Reporting Odds Ratio Analysis of Gemcitabine-Based Chemotherapy Regimens for Biliary and Pancreatic Cancer: Population-Level Toxicity Signals and Hypotheses for High-Altitude Generalizability
BackgroundGemcitabine-based chemotherapy is first-line for advanced biliary tract cancer (BTC) and pancreatic ductal adenocarcinoma (PDAC), but toxicity patterns are poorly defined at high altitude (>2,000 m). Clinical observations of heightened treatment toxicity at our high-altitude institution (X
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