bioRxiv / medRxiv
open access
Clinical history shapes the predictive value of polygenic risk
For most diseases, whether PRS improves prediction beyond clinical data remains unknown, as existing evidence is concentrated in a handful of conditions with established risk models. Using 900,000 participants from UK Biobank and FinnGen, we developed and validated models for predicting 150 diseases
Conceptio Open Archive
Analyze & explore related research in Conceptio
Connect this record directly into your research workflow or AI agent. Explore citations across open repositories, query full text, and export structured proof bundles.
This document is indexed with metadata only: full text is not available in the archive for this record. Open the official source ↗
Related documents
- Polygenic risk scores in neurological disorders: restless legs syndrome as a translational model#1001646
- Artificial intelligence in biomarker discovery for diseases: diagnostic and therapeutic prospects.#1097921
- Screening Biomarkers for Severe Lupus Based on Multi-omics Studies#1292771
- Promises and pitfalls of preimplantation genetic testing for polygenic disorders: a narrative review#113895
- Plasma proteomic profiles predict chronic obstructive pulmonary disease up to 16 years before onset: a multi-national, machine learning-guided biomarker discovery study#4938
Record · ID 1442504
Retrieved via Conceptio: every document is proof-bundled with source, license, and retrieval metadata.
Retrieved via Conceptio: every document is proof-bundled with source, license, and retrieval metadata.
Bring this data into your agent: Connect via MCP or API · 20 free credits to start · no card required
Read the Docs → · View CLI source on GitHub · Conceptio Open Knowledge Archive
Read the Docs → · View CLI source on GitHub · Conceptio Open Knowledge Archive