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Prevention of Recurrence of Crohn's Disease by Fecal Microbiota Therapy (FMT)

Boston Medical Center · 2015
ClinicalTrials.gov · Datasets · License: Public Domain · 2015
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crohn-s-diseasepreventionrecurrence
The objective of this trial is to assess if Fecal Microbiota Therapy (FMT) can reduce the risk of endoscopic recurrence of Crohn's disease (CD) in patients after intestinal resection. The specific outcomes of FMT to be examined are: 1) endoscopic appearance, 2) clinical symptoms, 3) safety and tolerability, and 4) microbial diversity. The research team hypothesizes that FMT will prevent establishment of "pro-inflammatory" microbiome after surgery, leading to a reduced probability of recurrence of macroscopic inflammation. It is also hypothesized that FMT will be safe and well-tolerated in these patients.
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