QANDLI DIABET 2-TURI RIVOJLANISHINING MOLEKULYAR-GENETIK XAVF OMILLARI

QANDLI DIABET 2-TURI RIVOJLANISHINING MOLEKULYAR-GENETIK XAVF OMILLARI | Zenodo Skip to main Communities My dashboard Log in Sign up Published April 27, 2026 | Version v1 Journal article Open QANDLI DIABET 2-TURI RIVOJLANISHINING MOLEKULYAR-GENETIK XAVF OMILLARI Authors/Creators Xalilova, Sevara (Data collector) 1 Show affiliations 1.

Andijon davlat tibbiyot instituti Gospital terapiya va endokrinologiya kafedrasi assistenti Andijon,Oʻzbekiston Description Ushbu maqolada qandli diabet 2-turining rivojlanishida muhim ahamiyatga ega bo‘lgan molekulyar-genetik omillar tahlil qilindi. Asosiy e’tibor FTO, AdipoR, VDR va LEPR genlarining funksional xususiyatlari, ularning polimorfizmlari hamda metabolik jarayonlarga ta’sir mexanizmlariga qaratildi. Tahlil natijalariga ko‘ra, ushbu genlar energiya almashinuvi, insulin sezgirligi, gormonal regulyatsiya va yog‘ to‘qimasi metabolizmini boshqarishda muhim rol o‘ynaydi. Genlarning o‘zaro ta’siri natijasida insulin rezistentligi va giperglikemiya rivojlanishi aniqlangan. Mazkur natijalar qandli diabet 2-turining patogenezini chuqurroq tushunish, erta diagnostika va shaxsiylashtirilgan davolash yondashuvlarini ishlab chiqishda muhim ahamiyatga ega. Files 611-618 Xalilova.pdf Files (409.3 kB) Name Size Download all 611-618 Xalilova.pdf md5:b85be9c595ba444f01a86574049b4613 409.3 kB Preview Download Additional details References 1. Frayling T.M., Timpson N.J., Weedon M.N. et al. A common variant in the FTO gene is associated with body mass index and predisposes to obesity. Nature. 2007; 447(7145): 1085–1088. 2. Kadowaki T., Yamauchi T., Kubota N. The physiological and pathophysiological role of adiponectin and adiponectin receptors in the metabolic syndrome and cardiovascular disease. Endocrine Reviews. 2006; 27(5): 439–451. 3. Pittas A.G., Lau J., Hu F.B., Dawson-Hughes B. The role of vitamin D and calcium in type 2 diabetes. Journal of Clinical Endocrinology & Metabolism. 2007; 92(6): 2017–2029. 4. Friedman J.M., Halaas J.L. Leptin and the regulation of body weight in mammals. Nature. 1998; 395(6704): 763–770. 5. McCarthy M.I. Genomics, type 2 diabetes, and obesity. New England Journal of Medicine. 2010; 363(24): 2339–2350. 46 Views 15 Downloads Show more details All versions This version Views Total views 46 46 Downloads Total downloads 15 15 Data volume Total data volume 7.0 MB 7.0 MB More info on how stats are collected.... Versions External resources Indexed in OpenAIRE Communities Keywords and subjects Keywords qandli diabet 2-turi, FTO geni, AdipoR, VDR, LEPR, insulin rezistentligi, semirish, gen polimorfizmi Details DOI DOI Badge DOI 10.5281/zenodo.19807499 Markdown [](https://doi.org/10.5281/zenodo.19807499) reStructuredText .. image:: https://zenodo.org/badge/DOI/10.5281/zenodo.19807499.svg :target: https://doi.org/10.5281/zenodo.19807499 HTML <a href="https://doi.org/10.5281/zenodo.19807499"><img src="https://zenodo.org/badge/DOI/10.5281/zenodo.19807499.svg" alt="DOI"></a> Image URL https://zenodo.org/badge/DOI/10.5281/zenodo.19807499.svg Target URL https://doi.org/10.5281/zenodo.19807499 Resource type Journal article Publisher Zenodo Published in JANUBIY OROL BO'YI TIBBIYOT JURNALI, 2(Maxsusu son), 611-618, ISSN: 3093-8740, 2026. Languages Uzbek Rights License Creative Commons Attribution 4.0 International The Creative Commons Attribution license allows re-distribution and re-use of a licensed work on the condition that the creator is appropriately credited. Read more Citation Export Technical metadata Created April 27, 2026 Modified April 27, 2026 Jump up About About Policies Infrastructure Principles Projects Roadmap Contact Blog Blog Support Help FAQ Developers REST API OAI-PMH Contribute GitHub Donate Funded by Powered by CERN Data Centre & InvenioRDM Status Privacy policy Cookie policy Terms of Use This site uses cookies. Find out more on how we use cookies Accept all cookies Accept only essential cookies

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