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The Endogenous Negative Allosteric Modulator, Lynx1, Inhibits Nicotinic Cholinergic Signaling in the Ventral Tegmental Area to Regulate Nicotine Reinforcement.
Neuronal nicotinic acetylcholine receptors (nAChRs) underlie many aspects of cholinergic signaling, including as essential contributors to learning and memory function. However, the functional impact of endogenous nAChR modulators remains largely unclear. Thus, the current investigations sought to d
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