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Beyond Alzheimer's story: How an engineered molecule gained an endogenous essence

Kopylov AT et al.
Europe PMC · Papers
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alzheimer-s-diseasemass-spectrometry
A hallmark of Alzheimer's disease (AD) is extra-neuronal protein aggregates formed mainly by the amyloid-β peptide (Aβ), that are deposited inside the brain as amyloid plaques. The formation of amyloid plaques requires participation of zinc ions. The 11-Glu-Val-His-His-14 region of Aβ is critical fo
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