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OPA1 controls mitochondrial dysfunction-driven liver fibrosis in MASLD

Yu, X. et al.
bioRxiv / medRxiv · Papers
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genetics
Progressive hepatic fibrosis is the principal determinant of morbidity and mortality in metabolic dysfunction-associated steatotic liver disease and steatohepatitis (MASLD/MASH). Mitochondrial dysfunction is a hallmark of MASH, and the release of mitochondrial damage-associated molecular patterns (m
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