DSSNA: An Open-Source GROMACS Module for Automated Analysis of Nucleic Acid Secondary and Tertiary Structure in Molecular Dynamics Simulations

This work presents DSSNA (Define Spatial Structure of Nucleic Acids) v2026, a free and open-source standalone GROMACS module for the automated analysis of nucleic acid structure based on atomic coordinates. DSSNA reproduces the core functionality of the X3DNA and DSSR approach while extending it to