Effectiveness of Peri-operative Combined Use of 2 Doses of Dexamethasone With Tranexamic Acid in Lower Limb Joint Replacements-A Randomized Controlled Trial.

The goal of this randomized controlled clinical trial is to investigate the effectiveness of peri operative use of 2 doses of dexamethasone with tranexamic acid in lower limb replacement, on post operative C-reactive protein (CRP), joint range of motion, fatigue, pain, hospital length of stay in male/female patients undergoing lower limb joint replacement, with pre op Hb above 10g/dL. The main question it aims to answer The peri operative use of 2 doses of dexamethasone with tranexamic acid in lower limb replacement, decrease the post operative CRP, fatigue, pain, hospital length of stay and increase the joint range of motion. Researcher will compare the two groups without knowing which group received either of 1 or 2 doses of Dexamethasone with TXA peri operatively. Patients will do answer the questions mentioned in questionnaire pre operatively, at post op 1st day, at 1st week and 4th week post discharge.